The Diocese of Scranton is a Latin Church ecclesiastical jurisdiction, or diocese, of the Catholic Church in northeastern Pennsylvania in the United States. It is a suffragan see of Archdiocese of Philadelphia, established on March 3, 1868.

The mother church of the Diocese of Scranton is St. Peter's Cathedral in Scranton.

The Diocese of Scranton includes the cities of Scranton, Wilkes-Barre, Williamsport, Hazleton, Nanticoke, Carbondale and Pittston.

The diocese comprises Lackawanna, Luzerne, Bradford, Susquehanna, Wayne, Tioga, Sullivan, Wyoming, Lycoming, Pike, and Monroe counties The area of the diocese is 8,487 square miles (21,980 km2).